KPTI — Karyopharm Therapeutics Inc.

KPTI closed at $0.8798 (+5.73%) on Oct 29, 2026. Active shelf registration (S-3, May 2026); dilution risk: high. Float: 20.8M shares. Latest SEC filing: SCHEDULE 13G/A on Oct 28, 2026.

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Karyopharm Therapeutics Inc is a commercial-stage pharmaceutical company focused on novel cancer therapies and dedicated to the discovery, development, and commercialization of drugs directed against nuclear export for the treatment of cancer and other diseases. The company conducts research focused on intracellular communication between the nucleus and cytoplasm and has developed small-molecule compounds that inhibit exportin 1 (XPO1), a nuclear export protein. It is focused on marketing XPOVIO (selinexor).

Company profile

• Sector: Healthcare
• Industry: Biotechnology
• Country: US
• Exchange: NASDAQ
• Employees: 228
• Website: https://www.karyopharm.com

Latest SEC filings for KPTI

• 2026-10-28SCHEDULE 13G/A
• 2026-10-148-K
• 2026-09-188-K
• 2026-09-118-K
• 2026-09-04SCHEDULE 13G
• 2026-08-318-K
• 2026-08-14SCHEDULE 13G/A
• 2026-08-1310-Q
• 2026-08-138-K
• 2026-08-12SCHEDULE 13G/A

Latest KPTI news

• 2026-10-28Four reporting parties each list the same stake in Karyopharm (KPTI).
• 2026-10-27Karyopharm Therapeutics (KPTI) Slides 7.51% to $0.45 as Shares Test Lower Support Zone
• 2026-10-26Karyopharm Therapeutics Inc (NASDAQ: KPTI) Share Price, KPTI Stock News, KPTI Share Price & Updates
• 2026-10-24Karyopharm Therapeutics stock sits 95.48 percent below target
• 2026-10-22What Is Powering the Rally in Karyopharm Therapeutics, Estrella Immunopharma, CytoSorbents, MoonLake Immunotherapeutics, FibroBiologics, Exicure, Biohaven and Profusa Stocks Today, and What Should Investors Know About the Catalysts?
• 2026-10-22Why Is Karyopharm Therapeutics (NASDAQ:KPTI) Penny Stock Up 12% Today When No News Has Appeared?
• 2026-10-01Karyopharm Therapeutics Reports Inducement Grant Under Nasdaq Listing Rule 5635(c)(4) Read article
• 2026-09-30Reviewing Alpha Cognition (NASDAQ:ACOG) & Karyopharm Therapeutics (NASDAQ:KPTI) Read article

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